Document Detail

Bronchoalveolar lavage fluid glutathione in intubated premature infants.
MedLine Citation:
PMID:  8346954     Owner:  NLM     Status:  MEDLINE    
Lower concentrations of uncorrected glutathione in the bronchoalveolar lavage fluid were found on the first day of life in seven infants who subsequently developed chronic lung disease when compared with 27 infants who did not require supplemental oxygen at 36 weeks' postconceptional age. The concentration of glutathione on the first day was independent of gestational age. These preliminary results suggest that glutathione accumulates in the lung epithelial lining fluid of preterm infants and that a relative deficiency may predispose to lung injury.
J Grigg; A Barber; M Silverman
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  69     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1993 Jul 
Date Detail:
Created Date:  1993-09-09     Completed Date:  1993-09-09     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  49-51     Citation Subset:  AIM; IM    
Royal Postgraduate Medical School, Hammersmith Hospital, London.
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MeSH Terms
Bronchoalveolar Lavage Fluid / chemistry*
Glutathione / analysis*
Infant, Newborn
Infant, Premature*
Infant, Premature, Diseases
Lung Diseases, Obstructive
Respiration, Artificial*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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