Document Detail


BRONCHIOLAR EMPHYSEMA. A REPORT OF A NECROPSIED CASE OF DIFFUSE BRONCHIOLECTASIS AND REVIEW OF THE LITERATURE.
MedLine Citation:
PMID:  14139997     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bronchiolar emphysema is a rare, insidious, progressive, bilateral pulmonary fibrosis with diffusion defect. Death follows in five to 10 years after the onset of symptoms because of respiratory failure, cor pulmonale or pneumothorax. In the 20 cases reviewed, the lungs typically showed bosselation of their pleural surfaces, giving the appearance and consistency of a liver involved by Laennec's cirrhosis. Cross sections showed honeycombing chiefly along the lung margins. Microscopically, cystic dilatation of terminal bronchioles was present, with obliteration of the remaining peripheral lung tissue by a dense pulmonary fibrosis. Hyperplasia of smooth muscle and elastica was prominent.Bronchiolar emphysema is a clinicopathologic entity, the etiology of which is unknown and likely multiple. Bronchiolectasis and superimposed recurrent infection are essential in its pathogenesis. Thickening of alveolar walls may play a decisive role in determining the characteristic site of the bronchiolar dilatation.
Authors:
L M JERRY; A C RITCHIE
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Canadian Medical Association journal     Volume:  90     ISSN:  0008-4409     ISO Abbreviation:  Can Med Assoc J     Publication Date:  1964 Apr 
Date Detail:
Created Date:  1964-08-01     Completed Date:  1996-12-01     Revised Date:  2010-06-22    
Medline Journal Info:
Nlm Unique ID:  0414110     Medline TA:  Can Med Assoc J     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  964-70     Citation Subset:  OM    
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MeSH Terms
Descriptor/Qualifier:
Bronchiectasis*
Osteoarthropathy, Secondary Hypertrophic*
Pathology*
Pneumothorax*
Prednisone*
Pulmonary Emphysema*
Pulmonary Fibrosis*
Pulmonary Heart Disease*
Respiratory Insufficiency*
Chemical
Reg. No./Substance:
53-03-2/Prednisone
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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