Document Detail


Bronchial sensitivity to histamine in former asthmatics: redevelopment of symptoms during a year of followup.
MedLine Citation:
PMID:  10883748     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this protocol was to study bronchial responsiveness in 23 former asthmatics who were free of symptoms for at least 5 years. Bronchial hyperreactivity (BHR) was evaluated with histamine challenge test and the results were compared with those of 20 normal subjects and 20 current asthmatic patients. Among the former asthmatics 65% fulfilled the criteria of BHR. During 1 year of followup, two former asthmatics redeveloped asthma symptoms. Interestingly, one patient had no BHR when initially tested. These findings suggest that the absence of BHR does not guarantee the nonrecurrence of asthma symptoms in former asthmatics.
Authors:
C Tálamo; J Velázquez; J M López
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of asthma : official journal of the Association for the Care of Asthma     Volume:  37     ISSN:  0277-0903     ISO Abbreviation:  J Asthma     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-07-17     Completed Date:  2000-07-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8106454     Medline TA:  J Asthma     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  371-5     Citation Subset:  IM    
Affiliation:
Service of Pulmonary Medicine, Hospital Universitario de Caracas, Escuela de Medicina Luis Razetti, Universidad Central de Venezuela.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Asthma / diagnosis*
Bronchial Hyperreactivity / diagnosis*
Bronchial Provocation Tests*
Female
Follow-Up Studies
Forced Expiratory Volume / drug effects
Histamine / diagnostic use*
Humans
Male
Recurrence
Chemical
Reg. No./Substance:
51-45-6/Histamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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