| Bronchial challenges and respiratory symptoms in elite swimmers and winter sport athletes: Airway hyperresponsiveness in asthma: its measurement and clinical significance. | |
| | |
MedLine Citation:
|
PMID: 20363843 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This study was aimed at the following: (1) the prevalence of airway hyperresponsiveness (AHR) and exercise-induced bronchoconstriction (EIB) in swimmers and winter sport athletes according to the previously recommended regulatory sport agencies criteria, (2) the relationship between respiratory symptoms and AHR/EIB, (3) the impact of the chosen cutoff value for AHR on its prevalence, and (4) the effect on the prevalence of the positive eucapnic voluntary hyperpnea (EVH) test of using the highest vs the lowest spirometric post-EVH values to calculate the magnitude of the airway response. We compared the prevalence of respiratory symptoms with responses to methacholine challenge and EVH in 45 swimmers, 45 winter sport athletes, and 30 controls. Two methacholine challenge cutoffs for AHR were analyzed: <or= 4 mg/mL (the sport agencies' criteria for AHR) and <or= 16 mg/mL. Sixty percent of swimmers, 29% of winter sport athletes, and 17% of controls had evidence of EIB or AHR (with the <or= 4 mg/mL criteria). Among athletes with a methacholine provocative concentration inducing a 20% decrease in the FEV(1) between 4 and 16 mg/mL, 43% of swimmers and 100% of winter sport athletes were symptomatic (P < .05). Prevalence of positive EVH tests were 39% in swimmers, 24% in winter sport athletes, and 13% in controls when the highest FEV(1) value measured at each time point post-EVH was used to identify maximal response for calculation of airway response, although these prevalences were higher if we used the lowest value. This study suggests that AHR/EIB is frequent in swimmers, whereas the frequently reported respiratory symptoms in winter sport athletes are often not related to AHR/EIB. Furthermore, the choice of methods for assessing methacholine challenge and EVH responses influences the prevalences of AHR and EIB. Trial registration: clinicaltrials.gov; Identifier NCT 00686491 and NCT 00686452. |
| | |
Authors:
|
Valérie Bougault; Julie Turmel; Louis-Philippe Boulet |
Related Documents
:
|
17321513 - Measurement of free igf-i saliva levels: perspectives in the detection of gh/igf axis i... 15474233 - Miscellaneous conditions about the elbow in athletes. 11708713 - The effectiveness of 0.5-lb increments in progressive resistance exercise. |
Publication Detail:
|
Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2010-04-02 |
Journal Detail:
|
Title: Chest Volume: 138 ISSN: 1931-3543 ISO Abbreviation: Chest Publication Date: 2010 Aug |
Date Detail:
|
Created Date: 2010-07-29 Completed Date: 2010-09-28 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0231335 Medline TA: Chest Country: United States |
Other Details:
|
Languages: eng Pagination: 31S-37S Citation Subset: AIM; IM |
Affiliation:
|
Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada. |
| Data Bank Information | |
Bank Name/Acc. No.:
|
ClinicalTrials.gov/NCT00686452; NCT00686491 |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Administration, Inhalation Adolescent Asthma, Exercise-Induced / diagnosis*, epidemiology, physiopathology Athletes* Bronchial Hyperreactivity / physiopathology* Bronchial Provocation Tests / methods* Bronchoconstriction / physiology* Bronchoconstrictor Agents / administration & dosage, diagnostic use Female Forced Expiratory Volume / physiology Humans Male Methacholine Chloride / administration & dosage, diagnostic use* Prevalence Quebec / epidemiology Risk Factors Swimming / physiology* Young Adult |
| Chemical | |
Reg. No./Substance:
|
0/Bronchoconstrictor Agents; 62-51-1/Methacholine Chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: In vitro evaluation of endotracheal tubes with intrinsic suction.
Next Document: Epidemiological Trend of Severe Sepsis in Taiwan from 1997 through 2006.