Document Detail

Bromocriptine improves reduced libido and potency in men receiving maintenance hemodialysis.
MedLine Citation:
PMID:  6357576     Owner:  NLM     Status:  MEDLINE    
Twenty-five men on maintenance hemodialysis commenced a placebo-controlled, double-blind, crossover trial of bromocriptine for erectile impotence. Eight patients on bromocriptine and one on placebo failed to complete the trial due to side-effects and 2 were withdrawn following renal transplantation. Libido or the frequency and/or quality of erections or both improved in 11 of the remaining 14 patients during bromocriptine treatment. A significant (P less than 0.01) improvement in patients' perception of sexual performance occurred on bromocriptine compared with placebo. The 3 patients in whom potency failed to improve had the lowest serum testosterone concentrations. Bromocriptine is usually effective in the management of impotence in males receiving maintenance hemodialysis provided pretreatment serum testosterone is above the lower end of the normal range, but side-effects are relatively common.
J W Muir; G M Besser; C R Edwards; L H Rees; W R Cattell; P Ackrill; L R Baker
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical nephrology     Volume:  20     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  1983 Dec 
Date Detail:
Created Date:  1984-01-26     Completed Date:  1984-01-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  308-14     Citation Subset:  IM    
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MeSH Terms
Bromocriptine / therapeutic use*
Clinical Trials as Topic
Double-Blind Method
Erectile Dysfunction / drug therapy*
Libido / drug effects*
Middle Aged
Renal Dialysis / adverse effects*
Testosterone / blood
Reg. No./Substance:
25614-03-3/Bromocriptine; 58-22-0/Testosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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