Document Detail


The Brody effect induced by premature ventricular complexes in the ovine heart.
MedLine Citation:
PMID:  21344793     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The QRS response of the electrocardiogram to bleeding has been a source of interest to the physiologist for more than a century. Studies in the dog, cat and chicken have shown a reduction in QRS amplitude in response to bleeding. This effect has been explained by the so-called Brody effect, in which the intraventricular mass of blood acts as a conducting medium, augmenting radial conduction, thus resulting in the subsequent reduction in QRS amplitude in conditions where the intraventricular mass of blood is reduced. The aim of this study was to evaluate whether the Brody effect will be present in the ovine heart and, furthermore, to evaluate if the right and left ventricles will demonstrate the same QRS change if the Brody effect is indeed present. This study clearly demonstrated that the Brody effect is present in the ovine heart. Furthermore, two unique aspects emanating from this study are firstly the fact that this is the first study to show that premature ventricular complexes are able to induce the Brody effect and, secondly that there is a very clear difference in the response of the right and the left ventricles when the Brody effect is induced in the ovine heart.
Authors:
J Ker; E C Webb; D Van Papendorp
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Onderstepoort journal of veterinary research     Volume:  76     ISSN:  0030-2465     ISO Abbreviation:  Onderstepoort J. Vet. Res.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2011-02-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401107     Medline TA:  Onderstepoort J Vet Res     Country:  South Africa    
Other Details:
Languages:  eng     Pagination:  443-8     Citation Subset:  IM    
Affiliation:
Department of Physiology, Faculty of Medicine, University of Pretoria, South Africa. jker@wol.co.za
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