| Brittle and ductile adjustable cement derived from calcium phosphate cement/polyacrylic acid composites. | |
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MedLine Citation:
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PMID: 18502499 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: Bone filler has been used over the years in dental and biomedical applications. The present work is to characterize a non-dispersive, fast setting, modulus adjustable, high bioresorbable composite bone cement derived from calcium phosphate-based cement combined with polymer and binding agents. This cement, we hope, will not swell in simulated body fluid and keep the osteogenetic properties of the dry bone and avoid its disadvantages of being brittle. METHODS: We developed a calcium phosphate cement (CPC) of tetracalcium phosphate/dicalcium phosphate anhydrous (TTCP/DCPA)-polyacrylic acid with tartaric acid, calcium fluoride additives and phosphate hardening solution. RESULTS: The results show that while composite, the hard-brittle properties of 25wt% polyacrylic acid are proportional to CPC and mixing with additives is the same as those of the CPC without polyacrylic acid added. With an increase of polyacrylic acid/CPC ratio, the 67wt% samples revealed ductile-tough properties and 100wt% samples kept ductile or elastic properties after 24h of immersion. The modulus range of this development was from 200 to 2600MPa after getting immersed in simulated body fluid for 24h. SIGNIFICANCE: The TTCP/DCPA-polyacrylic acid based CPC demonstrates adjustable brittle/ductile strength during setting and after immersion, and the final reaction products consist of high bioresorbable monetite/brushite/calcium fluoride composite with polyacrylic acid. |
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Authors:
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Wen-Cheng Chen; Chien-Ping Ju; Jen-Chyan Wang; Chun-Cheng Hung; Jiin-Huey Chern Lin |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-05-27 |
Journal Detail:
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Title: Dental materials : official publication of the Academy of Dental Materials Volume: 24 ISSN: 0109-5641 ISO Abbreviation: Dent Mater Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-10-28 Completed Date: 2009-01-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8508040 Medline TA: Dent Mater Country: England |
Other Details:
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Languages: eng Pagination: 1616-22 Citation Subset: D |
Affiliation:
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Faculty of Dentistry, Kaohsiung Medical University, 807 Kaohsiung, Taiwan. chenwc@kmu.edu.tw |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Absorbable Implants Acrylic Resins / chemistry* Bone Cements / chemical synthesis* Calcium Fluoride / chemistry Calcium Phosphates / chemistry* Dental Stress Analysis Elastic Modulus Hardness Materials Testing Phase Transition Tartrates / chemistry Tensile Strength Water |
| Chemical | |
Reg. No./Substance:
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0/Acrylic Resins; 0/Bone Cements; 0/Calcium Phosphates; 0/Tartrates; 0/tetracalcium phosphate; 526-83-0/tartaric acid; 7732-18-5/Water; 7757-93-9/dicalcium phosphate anhydrous; 7789-75-5/Calcium Fluoride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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