| Brief report: autism in individuals with Down syndrome. | |
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MedLine Citation:
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PMID: 16167094 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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As an off-shoot of a study examining the reliability and validity of an adapted version of the Pre-Linguistic Autism Diagnostic Observation Schedule (A-PL-ADOS), 13 individuals with Down syndrome with IQs ranging between 24 and 48 were administered the Autism Diagnostic Interview-Revised (ADI-R) and the A-PL-ADOS, which are well-validated interview and observational diagnostic measures. Three out of 13 met lifetime criteria on the ADI-R, but none of these three showed behavior that met the criterion for autism on the A-PL-ADOS (although two nearly did so). However, two individuals did meet the A-PL-ADOS criterion and showed behavior that fell only just short of meeting lifetime criteria on the ADI-R. Altogether, 5 individuals with Down syndrome may be considered to show an autism spectrum disorder. Of the remaining 8, some showed a few autistic features, and some showed none. The findings raise both methodological and conceptual issues. |
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Authors:
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Elizabeth M Starr; Sibel Kazak Berument; Megan Tomlins; Katerina Papanikolaou; Michael Rutter |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of autism and developmental disorders Volume: 35 ISSN: 0162-3257 ISO Abbreviation: J Autism Dev Disord Publication Date: 2005 Oct |
Date Detail:
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Created Date: 2006-02-22 Completed Date: 2006-03-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7904301 Medline TA: J Autism Dev Disord Country: United States |
Other Details:
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Languages: eng Pagination: 665-73 Citation Subset: IM |
Affiliation:
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MRC Child Psychiatry Unit, University of London, UK. estarr@uwindsor.ca |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Autistic Disorder / diagnosis, epidemiology* Child Down Syndrome / epidemiology* Female Humans Male Mental Retardation / diagnosis, epidemiology Questionnaires Severity of Illness Index |
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