| Briarane Diterpenes Diminish COX-2 Expression in Human Colon Adenocarcinoma Cells. | |
| | |
MedLine Citation:
|
PMID: 21438584 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Exploration of a soft coral (Briareum sp.) from Vanuatu led to the isolation of three new briaranes, designated brialalepolides A (1), B (2), and C (3). Compounds 2 and 3 reduced the expression of COX-2 in human colon adenocarcinoma cells, as well as in murine macrophage cells. This is significant because the metabolic products of COX-2 have been implicated in the pathogenesis of colon cancer and other diseases. |
| | |
Authors:
|
P Matthew Joyner; Amanda L Waters; Russell B Williams; Douglas R Powell; Naveena B Janakiram; Chinthalapally V Rao; Robert H Cichewicz |
Related Documents
:
|
14706924 - Dual excitation multi- fluorescence flow cytometry for detailed analyses of viability a... 15639564 - Single sperm cell isolation by laser microdissection. 21385594 - Interferon-γ modulates intestinal epithelial cell function in-vitro through a tgfβ-de... 20059164 - Transfer-arm evaporator cell for rapid loading and deposition of organic thin films. 8581064 - Buthionine sulfoximine enhances glutathione-but attenuates glutamate-stimulated cell pr... 22992254 - Cleavage pattern and fate map of the mesentoblast, 4d, in the gastropod crepidula: a ha... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-3-25 |
Journal Detail:
|
Title: Journal of natural products Volume: - ISSN: 1520-6025 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
|
Created Date: 2011-3-28 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7906882 Medline TA: J Nat Prod Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Natural Products Discovery Group, Department of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, 101 Stephenson Parkway, University of Oklahoma , Norman, Oklahoma 73019, United States. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: An Eight-Coordinate Vanadium Thiolate Complex with Charge Delocalization between V(V)-Thiolate and V...
Next Document: Metal-Organic Frameworks as Adsorbents for Hydrogen Purification and Precombustion Carbon Dioxide Ca...