| Bretylium tosylate in the management of recurrent ventricular fibrillation complicating acute myocardial infarction. | |
| | |
MedLine Citation:
|
PMID: 6898604 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Eighteen patients with recurrent ventricular fibrillation complicating acute myocardial infarction were treated with bretylium tosylate. All except one patient had been given therapeutic doses of lidocaine and some, in addition, had received other antiarrhythmic agents before bretylium. Bretylium therapy was initiated with intravenous administration of 5 mg/kg body weight and was usually maintained by administering the same dose every 6 to 8 hours by intramuscular route. Ten patients recovered while eight died. Only two of the survivors exhibited heart failure and none of them was in shock, while cardiogenic shock dominated the course of patients with fatal outcome. Postural hypotension invariably occurred but without any clinical deterioration of cardiac function. It is concluded that often bretylium tosylate is an effective therapeutic agent in suppression of recurrent or resistant ventricular fibrillation. |
| | |
Authors:
|
R W Dhurandhar; J Pickron; A M Goldman |
Related Documents
:
|
17162524 - Intrauterine myocardial infarction: unsuspected diagnosis in the delivery room. 1245504 - Counterpulsation in experimental cardiogenic shock with ventricular arrhythmias. the an... 18599494 - Decreasing incidence of critical limb ischemia after intra-aortic balloon pump counterp... 17133844 - Nitric oxide synthase inhibitors in post-myocardial infarction cardiogenic shock--an up... 6412894 - Lacunar infarcts in polycythaemia with raised packed cell volumes. 8678684 - The spanish monostrut study group: a ten-year experience with 8,599 implants. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Heart & lung : the journal of critical care Volume: 9 ISSN: 0147-9563 ISO Abbreviation: Heart Lung Publication Date: 1980 Mar-Apr |
Date Detail:
|
Created Date: 1980-05-14 Completed Date: 1980-05-14 Revised Date: 2006-08-28 |
Medline Journal Info:
|
Nlm Unique ID: 0330057 Medline TA: Heart Lung Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 265-70 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Bretylium Compounds / therapeutic use* Bretylium Tosylate / therapeutic use* Electrocardiography Female Humans Male Middle Aged Myocardial Infarction / complications* Ventricular Fibrillation / drug therapy*, etiology |
| Chemical | |
Reg. No./Substance:
|
0/Bretylium Compounds; 61-75-6/Bretylium Tosylate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Some properties of human pancreatic kallikrein and comparison with human trypsins and porcine kallik...
Next Document: Aneurysm precautions: a physiologic basis for minimizing rebleeding.