Document Detail


Breathing pattern in tetraplegics during exposure to hypoxia and hypercapnia.
MedLine Citation:
PMID:  8935145     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The question was investigated of whether thoracic feedback could play a role in shaping the tidal and frequency components of the breathing pattern. The changes in the breathing pattern of tetraplegic subjects were examined and compared with those of normal subjects during hypoxic and hypercapnic rebreathing tests, using data from our previous study. The breathing pattern was evaluated from diagramatic spirograms, constructed at an SaO2 80% and P(ET)CO2 of 55 mmHg. Chemical drive increased VT and shortened T1 and TE in both groups, but tetraplegics responded with a 60% smaller increase in VT. Since the mean inspiratory flow, VT/T1, was the same in either gas condition in both groups, the smaller VT in tetraplegics was due entirely to a shorter T1. These results show that ventilation in tetraplegics is more shallow and rapid, and it implicates thoracic feedback in modulation of the respiratory pattern.
Authors:
M Pokorski; T Morikawa; Y Honda
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Materia medica Polona. Polish journal of medicine and pharmacy     Volume:  27     ISSN:  0025-5246     ISO Abbreviation:  Mater Med Pol     Publication Date:    1995 Jul-Sep
Date Detail:
Created Date:  1996-12-23     Completed Date:  1996-12-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0236526     Medline TA:  Mater Med Pol     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  97-100     Citation Subset:  IM; S    
Affiliation:
Department of Neurophysiology, Polish Academy of Sciences, Warsaw.
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MeSH Terms
Descriptor/Qualifier:
Anoxia / physiopathology*
Humans
Hypercapnia / physiopathology*
Quadriplegia / physiopathology*
Respiration / physiology*
Retrospective Studies

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