Document Detail

Breathing pattern and efficiency of the respiratory muscles in healthy prematures and in prematures with respiratory distress syndrome.
MedLine Citation:
PMID:  6652259     Owner:  NLM     Status:  MEDLINE    
The relationship between the compliance of the respiratory system (Crs), measured by mouth occlusion technique, and the the breathing pattern, the central inspiratory activity, and the performance of the respiratory muscles respectively, was studied in healthy prematures and in prematures presenting with the respiratory distress syndrome. With decreasing Crs, respiratory rate, instantaneous minute-ventilation, airway pressure at 0.1 s after end-expiratory occlusion (P0.1), effective inspiratory impedance, the average rate of change of the pressure generated during the inspiratory effort against closed airways, and the work of breathing increased; inspiratory and expiratory times decreased overproportionally. We conclude that the changes in lung mechanics predispose prematures with a Crs of less than 1 ml X cmH2O-1 to develop respiratory failure because they cannot perform the respiratory work demanded by intact central regulation mechanisms.
C Popow; G Simbruner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bulletin européen de physiopathologie respiratoire     Volume:  19     ISSN:  0395-3890     ISO Abbreviation:  Bull Eur Physiopathol Respir     Publication Date:    1983 Nov-Dec
Date Detail:
Created Date:  1984-02-22     Completed Date:  1984-02-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7605263     Medline TA:  Bull Eur Physiopathol Respir     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  547-52     Citation Subset:  IM    
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MeSH Terms
Airway Resistance
Diaphragm / physiopathology*
Infant, Newborn
Infant, Premature*
Intercostal Muscles / physiopathology*
Lung Compliance
Lung Volume Measurements
Pectoralis Muscles / physiopathology*
Respiratory Distress Syndrome, Newborn / physiopathology*
Ventilation-Perfusion Ratio
Work of Breathing

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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