Document Detail


Breathing life into pathogens: the influence of oxygen on bacterial virulence and host responses in the gastrointestinal tract.
MedLine Citation:
PMID:  21166974     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The gastrointestinal tract provides a variety of environmental challenges to any bacterium seeking to successfully colonize or cause disease in a host. A major obstacle is the varied oxygen concentrations encountered at different sites in the intestine. Here we review the mechanisms bacterial pathogens utilize to sense oxygen within the gastrointestinal tract, and recent insights into how this acts as a signal to trigger virulence and to modulate host responses.
Authors:
Benoit Marteyn; Francesco Berlanda Scorza; Philippe J Sansonetti; Christoph Tang
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Publication Detail:
Type:  Journal Article     Date:  2010-12-19
Journal Detail:
Title:  Cellular microbiology     Volume:  13     ISSN:  1462-5822     ISO Abbreviation:  Cell. Microbiol.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883691     Medline TA:  Cell Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  171-6     Citation Subset:  IM    
Copyright Information:
© 2010 Blackwell Publishing Ltd.
Affiliation:
Unité de Pathogénie Microbienne Moléculaire, Institut Pasteur, 28 rue du Dr Roux, Paris Cédex 15, France.
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