Document Detail


Breath-hold 3D steady-state free precession coronary MRA compared with conventional X-ray coronary angiography.
MedLine Citation:
PMID:  16568438     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate the use of breath-hold three-dimensional (3D) steady-state free precession (SSFP) coronary magnetic resonance angiography (MRA) in patients with coronary artery disease (CAD) in comparison with conventional coronary x-ray angiography (XRA). MATERIALS AND METHODS: Twenty-eight patients with suspected CAD were examined with the use of a breath-hold 3D-SSFP-MRA sequence and conventional XRA. To assess the accuracy of MRA, two clinicians who were blinded to patient information independently reviewed the MRA and XRA data, which were presented in a randomized order. To identify discrepancies between MRA and XRA, and assess features of coronary lesions on MRA, two additional clinicians examined MRA and XRA data that were presented side by side, divided into proximal, mid, and distal segments, and compared them segment by segment. RESULTS: The sensitivity and specificity for diagnosing significant coronary stenoses (> 50% diameter narrowing) were 64% and 94%, respectively. At sites of coronary lesions identified on XRA, bright signals and enlarged vessel profiles, in addition to the characteristic narrow lumen, were frequently observed on MRA. CONCLUSION: Breath-hold SSFP coronary MRA has good specificity but inconclusive sensitivity in diagnosing significant coronary stenoses, and provides important image features for depicting coronary lesions.
Authors:
Liuquan Cheng; Yuangui Gao; Andrea I Guaricci; Suresh Mulukutla; Wei Sun; Fugeng Sheng; Thomas K Foo; Martin R Prince; Yi Wang
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  23     ISSN:  1053-1807     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-04-19     Completed Date:  2006-09-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  669-73     Citation Subset:  IM    
Copyright Information:
Copyright 2006 Wiley-Liss, Inc.
Affiliation:
Department of Radiology, Chinese PLA General Hospital, Beijing, China.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Coronary Angiography / methods*
Coronary Artery Disease / complications,  diagnosis*,  radiography
Coronary Stenosis / diagnosis
Female
Humans
Imaging, Three-Dimensional / methods*
Magnetic Resonance Angiography / methods*
Male
Middle Aged
Observer Variation
Reproducibility of Results
Respiration*
Sensitivity and Specificity
Grant Support
ID/Acronym/Agency:
HL062994/HL/NHLBI NIH HHS

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