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Breath analysis in asbestos-related disorders: a review of the literature and potential future applications.
MedLine Citation:
PMID:  21383477     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Asbestos usage was very common worldwide in the last century and continues in several countries today. Several diseases occur due to asbestos exposure, including malignant tumours such as malignant mesothelioma of the pleura and lung cancer, which have a very poor prognosis. Asbestos inhalation may also result in more benign conditions such as asbestosis (or pulmonary fibrosis due to asbestos), pleural plaques and pleural thickening. It is predicted that asbestos-associated mortality and morbidity will continue to increase, but methods for diagnosing asbestos-related disease are currently invasive and unsuitable for an increasingly elderly population. New non-invasive methods such as analysis of exhaled breath biomarkers e.g. exhaled nitric oxide (F(E)NO), exhaled breath condensate or of exhaled volatile organic compounds could potentially be extremely useful in these conditions. This article reviews the current literature on this topic and suggests areas for their application in the future.
Authors:
Eleanor A Chapman; Paul S Thomas; Deborah H Yates
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Publication Detail:
Type:  Journal Article     Date:  2010-08-27
Journal Detail:
Title:  Journal of breath research     Volume:  4     ISSN:  1752-7163     ISO Abbreviation:  J Breath Res     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2011-03-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101463871     Medline TA:  J Breath Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  034001     Citation Subset:  IM    
Affiliation:
Inflammation and Infection Research Centre, School of Medical Sciences, University of New South Wales, Kensington, NSW 2052, Australia.
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