Document Detail

Breastfeeding leads to lower blood pressure in 7-year-old Japanese children: Tohoku Study of Child Development.
MedLine Citation:
PMID:  22951522     Owner:  NLM     Status:  Publisher    
This study investigated the association between breastfeeding and both self-measured home blood pressure (HBP) and conventional blood pressure (CBP) in 7-year-old Japanese children. We obtained data pertaining to breastfeeding and blood pressure for 377 mother-offspring pairs from the Tohoku Study of Child Development, which is a prospective birth cohort study. Information on breastfeeding and other factors were obtained from parental questionnaires during the follow-up period. Based on the duration of breastfeeding as a major source of nutrition, mother-offspring pairs were divided into short-term (mean, 5.1 months) and long-term (mean, 11.3 months) breastfeeding groups. At the age of 7 years (84.4±1.8 months), each child's blood pressure was measured. The HBP in the long-term breastfeeding (LBF) group (92.8 mm Hg systolic/55.0 mm Hg diastolic) was significantly lower (P=0.006/0.03) than in the short-term breastfeeding group (94.5/56.3 mm Hg); however, there were no significant differences in the CBP measurements between the short- and LBF groups. Using multiple regression analysis, the duration of breastfeeding (greater than 8 months) was more strongly associated with HBP (P=0.01/0.06) than with CBP (P=0.4/0.8). Furthermore, the adjusted R-squared values for HBP (0.25/0.12) tended to be higher than those for CBP (0.07/0.04). These findings were independent of the birth weight. In conclusion, breastfeeding has a protective effect against elevated blood pressure even in young children, and subtle, but important, differences were precisely detected by self-measurements performed at home.Hypertension Research advance online publication, 6 September 2012; doi:10.1038/hr.2012.128.
Miki Hosaka; Kei Asayama; Jan A Staessen; Takayoshi Ohkubo; Katsuhisa Hayashi; Nozomi Tatsuta; Naoyuki Kurokawa; Michihiro Satoh; Takanao Hashimoto; Takuo Hirose; Taku Obara; Hirohito Metoki; Ryusuke Inoue; Masahiro Kikuya; Kunihiko Nakai; Yutaka Imai; Hiroshi Satoh
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-06
Journal Detail:
Title:  Hypertension research : official journal of the Japanese Society of Hypertension     Volume:  -     ISSN:  1348-4214     ISO Abbreviation:  Hypertens. Res.     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9307690     Medline TA:  Hypertens Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan.
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