Document Detail

Breastfeeding-associated hypernatremia: are we missing the diagnosis?
MedLine Citation:
PMID:  16140676     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To assess the incidence and complications of breastfeeding-associated hypernatremic dehydration among hospitalized neonates.
STUDY DESIGN: A retrospective study was conducted at Children's Hospital of Pittsburgh over a 5-year period, to identify otherwise healthy term and near-term (> or =35 weeks of gestation) breastfed neonates (<29 days of age) who were admitted with serum sodium concentrations of > or =150 mEq/L and no explanation for hypernatremia other than inadequate milk intake.
RESULTS: The incidence of breastfeeding-associated hypernatremic dehydration among 3718 consecutive term and near-term hospitalized neonates was 1.9%, occurring for 70 infants. These infants were born primarily to primiparous women (87%) who were discharged within 48 hours after birth (90%). The most common presenting symptom was jaundice (81%). Sixty-three percent of infants underwent sepsis evaluations with lumbar puncture. No infants had bacteremia or meningitis. Infants had hypernatremia of moderate severity (median: 153 mEq/L; range: 150-177 mEq/L), with a mean weight loss of 13.7%. Nonmetabolic complications occurred for 17% of infants, with the most common being apnea and/or bradycardia. There were no deaths.
CONCLUSION: Hypernatremic dehydration requiring hospitalization is common among breastfed neonates. Increased efforts are required to establish successful breastfeeding.
Michael L Moritz; Mioara D Manole; Debra L Bogen; J Carlos Ayus
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatrics     Volume:  116     ISSN:  1098-4275     ISO Abbreviation:  Pediatrics     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-05     Completed Date:  2005-12-13     Revised Date:  2014-07-29    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e343-7     Citation Subset:  AIM; IM    
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MeSH Terms
Apnea / etiology
Bradycardia / etiology
Breast Feeding / adverse effects*
Dehydration / etiology
Hypernatremia / diagnosis,  etiology*
Infant, Newborn
Weight Loss

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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