| Breastfeeding-associated hypernatremia: are we missing the diagnosis? | |
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MedLine Citation:
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PMID: 16140676 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To assess the incidence and complications of breastfeeding-associated hypernatremic dehydration among hospitalized neonates. Study DESIGN: A retrospective study was conducted at Children's Hospital of Pittsburgh over a 5-year period, to identify otherwise healthy term and near-term (> or =35 weeks of gestation) breastfed neonates (<29 days of age) who were admitted with serum sodium concentrations of > or =150 mEq/L and no explanation for hypernatremia other than inadequate milk intake. RESULTS: The incidence of breastfeeding-associated hypernatremic dehydration among 3718 consecutive term and near-term hospitalized neonates was 1.9%, occurring for 70 infants. These infants were born primarily to primiparous women (87%) who were discharged within 48 hours after birth (90%). The most common presenting symptom was jaundice (81%). Sixty-three percent of infants underwent sepsis evaluations with lumbar puncture. No infants had bacteremia or meningitis. Infants had hypernatremia of moderate severity (median: 153 mEq/L; range: 150-177 mEq/L), with a mean weight loss of 13.7%. Nonmetabolic complications occurred for 17% of infants, with the most common being apnea and/or bradycardia. There were no deaths. CONCLUSION: Hypernatremic dehydration requiring hospitalization is common among breastfed neonates. Increased efforts are required to establish successful breastfeeding. |
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Authors:
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Michael L Moritz; Mioara D Manole; Debra L Bogen; J Carlos Ayus |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pediatrics Volume: 116 ISSN: 1098-4275 ISO Abbreviation: Pediatrics Publication Date: 2005 Sep |
Date Detail:
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Created Date: 2005-09-05 Completed Date: 2005-12-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376422 Medline TA: Pediatrics Country: United States |
Other Details:
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Languages: eng Pagination: e343-7 Citation Subset: AIM; IM |
Affiliation:
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Division of Nephrology, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. michael.moritz@chp.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Apnea
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etiology Bradycardia / etiology Breast Feeding / adverse effects* Dehydration / etiology Humans Hypernatremia / diagnosis, etiology* Infant, Newborn Weight Loss |
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