Document Detail

Breast-milk intake of 9-10-mo-old rural infants given a ready-to-use complementary food in South Kivu, Democratic Republic of Congo.
MedLine Citation:
PMID:  21450933     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Lipid-based ready-to-use foods are currently used for infant feeding, but their potential effect on breast-milk intake is not well documented.
OBJECTIVE: The objective was to assess the breast-milk intake of 9-10-mo-old infants given either a ready-to-use complementary food (RUCF) paste or a standard corn-soy blend (UNIMIX) porridge in South Kivu, Democratic Republic of Congo.
DESIGN: Infants were randomly assigned at 6 mo of age to receive either RUCF (n = 700) or UNIMIX (n = 700) for 6 mo. Breast-milk intake was measured at 9-10 mo in a subsample of 58 infants (29 from each group). Mothers received a dose of ≈30 g deuterium oxide. Predose and postdose saliva samples were collected from both mothers and infants over 2 wk. Breast-milk intake (g/d) was measured from saliva samples by using infrared spectroscopy.
RESULTS: Mean (±SD) breast-milk intake was not significantly (P = 0.69) different between the 2 groups: RUCF (705 ± 236 g/d) and UNIMIX (678 ± 285 g/d). Mean (±SD) nonmilk oral water intakes were 338.3 ± 251.1 and 336.4 ± 227.2 g/d for RUCF and UNIMIX, respectively (P = 0.98).
CONCLUSIONS: No differences in breast-milk intake were observed between infants consuming either RUCF or UNIMIX. The deuterium-dose-to-the-mother dilution technique is an affordable technique that we recommend for periodic evaluation of breast-milk intake in resource-poor settings. This trial is registered at as ISRCTN20267635.
Victor O Owino; Paluku Bahwere; Ghislain Bisimwa; Christine M Mwangi; Steve Collins
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2011-03-30
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  93     ISSN:  1938-3207     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-23     Completed Date:  2011-07-28     Revised Date:  2011-08-29    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1300-4     Citation Subset:  AIM; IM    
Valid Nutrition, Nairobi, Kenya.
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MeSH Terms
Breast Feeding*
Democratic Republic of the Congo
Deuterium Oxide / administration & dosage
Dietary Fats / administration & dosage
Infant Food*
Infant Nutritional Physiological Phenomena*
Milk, Human* / metabolism
Rural Population
Spectrophotometry, Infrared
Water / administration & dosage
Zea mays
Reg. No./Substance:
0/Dietary Fats; 7732-18-5/Water; 7789-20-0/Deuterium Oxide

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