Document Detail

Breast milk antibodies to foods in relation to maternal diet, maternal atopy and the development of atopic disease in the baby.
MedLine Citation:
PMID:  2592118     Owner:  NLM     Status:  MEDLINE    
Breast milk samples were collected from 152 women during the first week after delivery. The levels of IgG and IgA antibodies to beta-lactoglobulin, ovalbumin and gliadin were assessed with an enzyme-linked immunosorbent assay (ELISA). The breast milk antibody levels did not differ significantly between mothers on a strictly cow's milk and egg-free diet, and mothers taking these foods. Moreover, the colostral food antibody levels did not differ significantly between atopic and non-atopic mothers. Neither was there any correlation between the colostral antibody levels and the development of atopic disease in the baby. I conclude that maternal antigen avoidance during late pregnancy does not affect the food antibody levels in colostrum. High levels of food antibodies in a colostrum sample seem not to offer protection against food allergy in the child.
K Fälth-Magnusson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International archives of allergy and applied immunology     Volume:  90     ISSN:  0020-5915     ISO Abbreviation:  Int. Arch. Allergy Appl. Immunol.     Publication Date:  1989  
Date Detail:
Created Date:  1990-01-24     Completed Date:  1990-01-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0404561     Medline TA:  Int Arch Allergy Appl Immunol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  297-300     Citation Subset:  IM    
Department of Pediatrics, Faculty of Health Sciences, University of Linköping, Sweden.
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MeSH Terms
Colostrum / immunology
Food Hypersensitivity / immunology*
Gliadin / immunology
Hypersensitivity / immunology*
Infant, Newborn
Lactoglobulins / immunology
Milk / immunology
Milk, Human / immunology*
Ovalbumin / immunology
Prospective Studies
Reg. No./Substance:
0/Lactoglobulins; 9006-59-1/Ovalbumin; 9007-90-3/Gliadin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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