Document Detail

Breast implantation and the incidence of upper extremity somatic complaints.
MedLine Citation:
PMID:  9143425     Owner:  NLM     Status:  MEDLINE    
Attention has been drawn to elevated laboratory tests of inflammation as indicators of a possible reaction to silicone breast implants. These patients have complaints of joint pain, pain, and myalgia that were possibly caused by a reaction to silicone. This study is a retrospective review of 100 consecutive patients (79 female, 21 male) who were evaluated because of a purported industrial injury to the upper extremity. Patients were examined by a single examiner and all had laboratory screening for indicators of inflammation (sedimentation rate, anti-nuclear antibody levels, C-reactive protein, anti-streptolysin, rheumatic factor), endocrine abnormalities (thyroid panel), and serum glucose. None of the patients had any history of breast augmentation with any implant. Of the 79 female patients, 50 had an identifiable clinical diagnosis and 18 of them had elevation of at least one of the indicators of inflammation. The remaining 29 did not have an identifiable diagnosis and 21 of them had elevation of at least one indicator of inflammation (P < 0.01). There were 74 out of 79 females with subjective complaints of upper extremity pain, joint pain, and aching. Forty-five of these patients had an identifiable diagnosis and 17 of them had elevation of at least one inflammatory indicator. Of the 74 female patients, 29 had no identifiable diagnosis and 21 of them had elevation of at least one inflammatory indicator (P < 0.01). In summary, there were a high number of female patients with complaints of upper extremity symptoms with no prior exposure to silicone from breast implantation. There was a statistically significant correlation in these patients who had no identifiable diagnosis and elevated indicators in inflammation. This study suggests these markers of inflammation should not be used as indicators of a reaction to silicone from breast implantation in patients with upper extremity subjective complaints.
M Kulick; H Daneshmand
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Aesthetic plastic surgery     Volume:  21     ISSN:  0364-216X     ISO Abbreviation:  Aesthetic Plast Surg     Publication Date:    1997 Mar-Apr
Date Detail:
Created Date:  1997-05-30     Completed Date:  1997-05-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7701756     Medline TA:  Aesthetic Plast Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  105-9     Citation Subset:  IM    
Department of Plastic and Reconstructive Surgery, Saint Francis Memorial Hospital, San Francisco, California 94108, USA.
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MeSH Terms
Breast Implants / adverse effects*
Connective Tissue Diseases / complications,  diagnosis,  etiology*
Inflammation / complications
Middle Aged
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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