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Breast-fed infants have higher leptin values than formula-fed infants in the first four months of life.
MedLine Citation:
PMID:  15570990     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Leptin is a hormone present in breast milk, which regulates food intake and energy metabolism. AIM: To investigate whether leptin levels are different in breast-fed (BF) or formula-fed (FF) infants in the first months of life. METHODS: We evaluated serum leptin by radio-immunoassay and anthropometric parameters in 51 infants at the average age of 62.8+/-30 days, 25 exclusively BF and 26 exclusively FF. RESULTS: Leptin serum values were higher in BF (7.1+/-10.4 ng/ml) than in FF (3.7+/-3.87 ng/ml) infants (p <0.05). Leptin values were higher in females (6.9+/-9.87 ng/ml) than in males (3.5+/-3.88 ng/ml) (p <0.05). No differences were found in anthropometric measurements and body mass index. CONCLUSION: The kind of feeding might be a factor affecting serum leptin concentration in term infants. The long-term consequences of this difference between BF and FF infants and leptin's role in promoting obesity later in life are unknown.
F Savino; G E Nanni; S Maccario; M Costamagna; R Oggero; L Silvestro
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric endocrinology & metabolism : JPEM     Volume:  17     ISSN:  0334-018X     ISO Abbreviation:  J. Pediatr. Endocrinol. Metab.     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-12-01     Completed Date:  2005-02-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508900     Medline TA:  J Pediatr Endocrinol Metab     Country:  England    
Other Details:
Languages:  eng     Pagination:  1527-32     Citation Subset:  IM    
Dipartimento di Scienze Pediatriche e dell'Adolescenza, Ospedale Infantile Regina Margherita, Università di Torino, Italy.
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MeSH Terms
Body Mass Index
Breast Feeding*
Infant Food*
Infant, Newborn
Leptin / blood*
Sex Characteristics
Reg. No./Substance:

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