Document Detail


Breast cancer in a male with ankylosing spondylitis treated with TNFalpha antagonists.
MedLine Citation:
PMID:  19457692     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 72-year-old male with a 4-year history of TNFalpha antagonist therapy (infliximab and etanercept) for ankylosing spondylitis was diagnosed with breast cancer. He had a family history of breast cancer. The low incidence and considerable severity of breast cancer in males, genetic risk factors, and potential role for TNFalpha antagonist therapy are discussed.
Authors:
Laila El Mansouri; Tifenn Couchouron; Guillaume Le Roux; Catherine Dugast; Françoise Burtin; Jean-David Albert; Aleth Perdriger; Najia Hajjaj Hassouni; Gérard Chalès
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-05-19
Journal Detail:
Title:  Joint, bone, spine : revue du rhumatisme     Volume:  76     ISSN:  1778-7254     ISO Abbreviation:  Joint Bone Spine     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-07-14     Completed Date:  2009-11-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100938016     Medline TA:  Joint Bone Spine     Country:  France    
Other Details:
Languages:  eng     Pagination:  421-3     Citation Subset:  IM    
Affiliation:
Service de Rhumatologie, CHU Rennes, France. la_mansouri1@yahoo.fr
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MeSH Terms
Descriptor/Qualifier:
Aged
Antibodies, Monoclonal / adverse effects,  therapeutic use*
Breast Neoplasms, Male / diagnosis*,  genetics,  physiopathology
Genes, BRCA2
Genetic Predisposition to Disease
Humans
Immunoglobulin G / adverse effects,  therapeutic use*
Male
Receptors, Tumor Necrosis Factor / therapeutic use*
Risk Factors
Spondylitis, Ankylosing / drug therapy*
Tumor Necrosis Factor-alpha / antagonists & inhibitors*,  physiology
Chemical
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Immunoglobulin G; 0/Receptors, Tumor Necrosis Factor; 0/Tumor Necrosis Factor-alpha; 0/infliximab; 185243-69-0/TNFR-Fc fusion protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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