| Breast MR with special focus on DW-MRI and DCE-MRI. | |
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MedLine Citation:
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PMID: 22185766 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The use of magnetic resonance imaging (MRI) for the assessment of breast lesions was first described in the 1970s; however, its wide application in clinical routine is relatively recent. The basic principles for diagnosis of a breast lesion rely on the evaluation of signal intensity in T2-weighted sequences, on morphologic assessment and on the evaluation of contrast enhancement behaviour. The quantification of dynamic contrast behaviour by dynamic contrast-enhanced (DCE) MRI and evaluation of the diffusivity of water molecules by means of diffusion-weighted MRI (DW-MRI) have shown promise in the work-up of breast lesions. Therefore, breast MRI has gained a role for all indications that could benefit from its high sensitivity, such as detection of multifocal lesions, detection of contralateral carcinoma and in patients with familial disposition. Breast MRI has been shown to have a role in monitoring of neoadjuvant chemotherapy, for the evaluation of therapeutic results during the course of therapy. Breast MRI can improve the determination of the remaining tumour size at the end of therapy in patients with a minor response. DCE-MRI and DW-MRI have shown potential for improving the early assessment of tumour response to therapy and the assessment of residual tumour after the end of therapy. Breast MRI is important in the postoperative work-up of breast cancers. High sensitivity and specificity have been reported for the diagnosis of recurrence; however, pitfalls such as liponecrosis and changes after radiation therapy have to be carefully considered. |
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Authors:
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G Petralia; L Bonello; F Priolo; P Summers; M Bellomi |
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Publication Detail:
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Type: Journal Article Date: 2011-10-03 |
Journal Detail:
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Title: Cancer imaging : the official publication of the International Cancer Imaging Society Volume: 11 ISSN: 1470-7330 ISO Abbreviation: Cancer Imaging Publication Date: 2011 |
Date Detail:
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Created Date: 2011-12-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101172931 Medline TA: Cancer Imaging Country: England |
Other Details:
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Languages: eng Pagination: S74 Citation Subset: IM |
Affiliation:
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Division of Radiology, European Institute of Oncology, Via Ripamonti 435, 20141, Milan, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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