| Breast lesions: quantitative elastography with supersonic shear imaging--preliminary results. | |
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MedLine Citation:
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PMID: 20505064 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To determine the appearance of breast lesions at quantitative ultrasonographic (US) elastography by using supersonic shear imaging (SSI) and to assess the correlation between quantitative values of lesion stiffness and pathologic results, which were used as the reference standard. MATERIALS AND METHODS: This study was approved by the French National Committee for the Protection of Patients Participating in Biomedical Research Programs. All patients provided written informed consent. Conventional US and SSI quantitative elastography were performed in 46 women (mean age, 57.6 years; age range, 38-71 years) with 48 breast lesions (28 benign, 20 malignant; mean size, 14.7 mm); pathologic results were available in all cases. Quantitative lesion elasticity was measured in terms of the Young modulus (in kilopascals). Sensitivity, specificity, and area under the curve were obtained by using a receiver operating characteristic curve analysis to assess diagnostic performance. RESULTS: All breast lesions were detected at SSI. Malignant lesions exhibited a mean elasticity value of 146.6 kPa +/- 40.05 (standard deviation), whereas benign ones had an elasticity value of 45.3 kPa +/- 41.1 (P < .001). Complicated cysts were differentiated from solid lesions because they had elasticity values of 0 kPa (no signal was retrieved from liquid areas). CONCLUSION: SSI provides quantitative elasticity measurements, thus adding complementary information that potentially could help in breast lesion characterization with B-mode US. |
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Authors:
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Alexandra Athanasiou; Anne Tardivon; Mickael Tanter; Brigitte Sigal-Zafrani; Jeremy Bercoff; Thomas Deffieux; Jean-Luc Gennisson; Mathias Fink; Sylvia Neuenschwander |
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Publication Detail:
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Type: Journal Article Date: 2010-05-26 |
Journal Detail:
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Title: Radiology Volume: 256 ISSN: 1527-1315 ISO Abbreviation: Radiology Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-06-24 Completed Date: 2010-07-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: United States |
Other Details:
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Languages: eng Pagination: 297-303 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, Institut Curie, 26 rue d'Ulm, Paris Cedex 05, France. alexandra.athanasiou@curie.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Area Under Curve Breast Neoplasms / ultrasonography* Diagnosis, Differential Elasticity Imaging Techniques / methods* Female Humans Image Interpretation, Computer-Assisted / methods Middle Aged ROC Curve Sensitivity and Specificity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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