Document Detail

Breakthrough in treating gestational diabetes mellitus.
MedLine Citation:
PMID:  15317230     Owner:  NLM     Status:  MEDLINE    
QUESTION: I practise in a remote community in Manitoba. Quite a few of my patients experience gestational diabetes. Their compliance with the insulin regimen is abysmal. Can I give them an oral medication?
ANSWER: Recent studies have indicated that glyburide does not cross the human placenta and that its effectiveness and safety profiles are similar to those of insulin.
Gideon Koren
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian family physician Médecin de famille canadien     Volume:  50     ISSN:  0008-350X     ISO Abbreviation:  Can Fam Physician     Publication Date:  2004 Jul 
Date Detail:
Created Date:  2004-08-19     Completed Date:  2004-09-14     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  0120300     Medline TA:  Can Fam Physician     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  987, 989     Citation Subset:  IM    
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MeSH Terms
Diabetes, Gestational / drug therapy*
Glyburide / administration & dosage,  pharmacokinetics,  therapeutic use*
Hypoglycemic Agents / administration & dosage,  pharmacokinetics,  therapeutic use*
Insulin / therapeutic use
Patient Compliance
Rural Health Services
Reg. No./Substance:
0/Hypoglycemic Agents; 0/Insulin; 10238-21-8/Glyburide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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