Document Detail


Breakpoints in variant Philadelphia translocations in chronic myeloid leukemia.
MedLine Citation:
PMID:  3463367     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To date, 327 cases of variant Philadelphia translocations found in chronic myeloid leukemia have been described. A statistical analysis using the Monte Carlo simulation was performed to determine which chromosomal bands were preferentially involved in variant Philadelphia translocations. The results showed that twenty-eight bands were significantly rearranged (P less than 0.05).
Authors:
M De Braekeleer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Blut     Volume:  53     ISSN:  0006-5242     ISO Abbreviation:  Blut     Publication Date:  1986 Oct 
Date Detail:
Created Date:  1986-11-18     Completed Date:  1986-11-18     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0173401     Medline TA:  Blut     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  301-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Chromosome Banding
Genetic Variation
Humans
Leukemia, Myeloid / genetics*
Philadelphia Chromosome*
Translocation, Genetic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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