Document Detail


Brainstem lesion in Aicardi-Goutières syndrome.
MedLine Citation:
PMID:  9744637     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Aicardi-Goutières syndrome is characterized by the calcification of basal ganglia, leukodystrophy, and lymphocytosis in cerebrospinal fluid. No brainstem lesion has been described. We report a Japanese girl who presented with delayed development and microcephalus at early infancy. Magnetic resonance imaging revealed T2-weighted high intensity in the cerebral white matter and brainstem, and nerve conduction velocity was delayed in the central nervous system, indicating that she manifested dysmyelination in the brainstem white matter similar to that in the cerebral white matter.
Authors:
M Kato; R Ishii; A Honma; H Ikeda; K Hayasaka
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric neurology     Volume:  19     ISSN:  0887-8994     ISO Abbreviation:  Pediatr. Neurol.     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-12-04     Completed Date:  1998-12-04     Revised Date:  2006-05-23    
Medline Journal Info:
Nlm Unique ID:  8508183     Medline TA:  Pediatr Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  145-7     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Yamagata University School of Medicine, Iida-nishi, Japan.
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MeSH Terms
Descriptor/Qualifier:
Basal Ganglia Diseases / diagnosis*
Brain Diseases / diagnosis*
Brain Stem / pathology,  radiography*
Calcinosis / diagnosis*
Female
Humans
Infant
Lymphocytosis / cerebrospinal fluid,  diagnosis*
Magnetic Resonance Imaging*
Syndrome
Tomography, X-Ray Computed*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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