Document Detail

Brainstem auditory response findings in term neonates in intensive care unit.
MedLine Citation:
PMID:  22880629     Owner:  NLM     Status:  Publisher    
Abstract Objectives: Whether term infants in neonatal intensive care unit (NICU) have brainstem auditory abnormalities remains to be determined. This study aimed to detect any abnormality in brainstem auditory function in term neonates who are admitted to neonatal intensive care unit (NICU). Methods:From a NICU we recruited 55 term neonates with various perinatal problems. They were studied during the first week after birth using brainstem auditory evoked response, and the results were compared with normal term controls. Results: Wave I and III latencies and I-III interpeak interval of the evoked response in the NICU term neonates were similar to those in the controls. Wave V latency and I-V and III-V interpeak intervals tended to be increased at 21/s clicks. The increase was more obvious at higher rates 51 and 91/s. Analysis of variance revealed that at 21/s clicks only III-V interval was significantly increased (P <0.05). At 51 and 91/s clicks, wave V latency and III-V and I-V intervals were significantly increased (P <0.05-0.01). The rates of the abnormalities were seen more at higher than at lower click rates. The amplitudes of waves I, III and V in the NICU neonates were all slightly reduced, but none differed significantly from the controls. Conclusions: There are some abnormalities in brainstem auditory brainstem response in term neonates in NICU, suggesting functional abnormality in the auditory brainstem in NICU infants.
Ze D Jiang; Chao Chen; Andrew R Wilkinson
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-13
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Division of Neonatology, Children's Hospital of Fudan University, Shanghai, China.
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