Document Detail


Brainstem auditory evoked responses and quantitative saccade studies in multiple sclerosis: a comparative evaluation.
MedLine Citation:
PMID:  6568939     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Brainstem auditory evoked responses (BAERs) and quantitative saccadic eye movement studies provide information on the integrity of pathways traversing the brainstem. To compare the relative yield of abnormalities with the two techniques, the findings in a group of 46 patients with clinically definite, probable or suspected multiple sclerosis, in whom both procedures were performed, were analysed. BAERs were abnormal in 18 cases (39%), the abnormalities being subclinical in 10 (22%). One or more saccade parameters (reaction time, velocity, accuracy) were abnormal in 31 cases (67%), the abnormalities being subclinical in 19 (41%). When the results of both procedures were taken into account, the overall incidence of abnormalities was 76% and the overall incidence of subclinical abnormalities was 52%. Abnormalities were found with both techniques in 15 cases and with neither technique in 12 cases. Sixteen cases with normal BAERs had an abnormal saccade study, but only three cases with a normal saccade study had abnormal BAERs. It is concluded that BAERs and quantitative saccade studies have a complementary role in the investigation of patients with multiple sclerosis.
Authors:
W Knezevic; F L Mastaglia; J L Black; D W Collins
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and experimental neurology     Volume:  20     ISSN:  0196-6383     ISO Abbreviation:  Clin Exp Neurol     Publication Date:  1984  
Date Detail:
Created Date:  1985-02-20     Completed Date:  1985-02-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7909724     Medline TA:  Clin Exp Neurol     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  175-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Brain Stem / physiopathology*
Evoked Potentials, Auditory
Eye Movements*
Female
Humans
Male
Middle Aged
Multiple Sclerosis / physiopathology*
Saccades*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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