| Brainstem auditory evoked responses in 200 patients with multiple sclerosis. | |
| | |
MedLine Citation:
|
PMID: 7369720 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Brainstem auditory evoked responses (BAERs) were recorded from 202 patients with definite, probable, or possible multiple sclerosis (MS). Definitions of abnormality were based only on interwave separations and the wave I/wave V amplitude ratio. Thirty-two percent of the patients had abnormal BAERs, and the presence of clinically unsuspected lesions was revealed by BAER abnormalities in 7.4%. Thirty-five percent of the patients who had nystagmus and 53% of those who had internuclear ophthalmoplegia at the time of testing had BAER abnormalities. Forty-five percent of the abnormalities were elicited with stimulation of one ear only, stressing the importance of monaural stimulation. Click rates faster than 10 per second did not reveal abnormalities undetected at slower rates. BAERs were normal by these criteria in patients with labyrinthine diseases and amyotrophic lateral sclerosis. Thus, the BAER in MS can (1) confirm the presence of central lesions in patients with suspected brainstem involvement, (2) document the presence of clinically unsuspected lesions, and (3) be followed over time to provide possible assistance in evaluating the effectiveness of therapeutic measures. The BAER is a useful tool in the diagnosis and management of MS. |
| | |
Authors:
|
K H Chiappa; J L Harrison; E B Brooks; R R Young |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Annals of neurology Volume: 7 ISSN: 0364-5134 ISO Abbreviation: Ann. Neurol. Publication Date: 1980 Feb |
Date Detail:
|
Created Date: 1980-06-16 Completed Date: 1980-06-16 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7707449 Medline TA: Ann Neurol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 135-43 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acoustic Stimulation
/
methods Auditory Pathways / physiopathology* Brain Stem / physiopathology Diagnosis, Differential Diplopia / complications Evoked Potentials Evoked Potentials, Auditory Humans Median Nerve / physiopathology Multiple Sclerosis / complications, diagnosis*, physiopathology Nystagmus, Pathologic / complications Ophthalmoplegia / complications Reaction Time |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Familial stroke syndrome associated with mitral valve prolapse.
Next Document: Cold face test in the assessment of trigeminal-brainstem-vagal function in humans.