| Brainstem involvement in Sjögren's syndrome-related sensory neuronopathy. | |
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MedLine Citation:
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PMID: 19558581 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE: Sensory neuronopathies (SN) are peripheral nervous system disorders associated with degeneration of dorsal root ganglion neurons. Magnetic resonance imaging (MRI) studies have shown abnormalities limited to T2-weighted high signal intensity in the posterior columns. METHODS AND RESULTS: A 65-year-old woman with Sjögren syndrome had slowly progressive unsteadiness of gait and limb paresthesias. A blink reflex examination suggested a paramedian brainstem lesion, confirmed by MRI. CONCLUSIONS: Sjögren's syndrome-related SN may be associated with a more diffuse immune-mediated aggression, involving also the brainstem, and leading to some of the blink reflex abnormalities observed in nonparaneoplastic SN. |
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Authors:
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Alfredo Damasceno; Marcondes C França; Verônica A Zanardi; Anamarli Nucci |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of neuroimaging : official journal of the American Society of Neuroimaging Volume: 20 ISSN: 1552-6569 ISO Abbreviation: J Neuroimaging Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-11-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9102705 Medline TA: J Neuroimaging Country: United States |
Other Details:
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Languages: eng Pagination: 397-9 Citation Subset: IM |
Copyright Information:
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Copyright © 2009 by the American Society of Neuroimaging. |
Affiliation:
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Departments of Neurology, School of Medicine, State University of Campinas (UNICAMP), Campinas, Brazil. alfredodamasceno@hotmail.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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