| Brainstem hyperperfusion syndrome after intravenous thrombolysis: a case report. | |
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MedLine Citation:
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PMID: 20331500 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE: Recombinant tissue plasminogen activator (rtPA)-associated hyperperfusion syndrome in brainstem after acute stroke has not yet been reported. The current report demonstrates that rtPA-associated hyperperfusion syndrome can be a cause of clinical deterioration following improvement (DFI) after rtPA in acute stroke. METHODS: We observed a transient DFI in a 59-year-old man with acute ischemic stroke who received rtPA. The phenomenon was assessed by magnetic resonance imaging (MRI) with diffusion-weighted image (DWI) and a series of transcranial Doppler scan evaluating changes in the basilar arterial flow. RESULTS: We demonstrated a reversible hyperintensity at pons on DWI as well as a transient increase in basilar arterial flow on Doppler scan suggesting the occurrence of vasogenic edema and hyperperfusion at brainstem. CONCLUSIONS: rtPA-associated hyperperfusion can occur at brainstem causing transient neurological deficits. It can be a cause of DFI in addition to reocclusion after recanalization. |
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Authors:
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Chi-Ieong Lau; Li-Ming Lien; Wei-Hung Chen |
Publication Detail:
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Type: Journal Article Date: 2010-03-17 |
Journal Detail:
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Title: Journal of neuroimaging : official journal of the American Society of Neuroimaging Volume: 21 ISSN: 1552-6569 ISO Abbreviation: J Neuroimaging Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-06-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9102705 Medline TA: J Neuroimaging Country: United States |
Other Details:
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Languages: eng Pagination: 277-9 Citation Subset: IM |
Copyright Information:
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© 2010 by the American Society of Neuroimaging. |
Affiliation:
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From the Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (CIL, LML, WHC); and College of Medicine, Taipei Medical University, Taipei, Taiwan (LML, WHC). |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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