Document Detail


Brain weight-body weight ratio in sudden infant death syndrome revisited.
MedLine Citation:
PMID:  22619376     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
AimsTo determine whether the brain-body weight ratio is increased in sudden infant death syndrome (SIDS).MethodsReview of autopsy files from Forensic Science SA, South Australia was undertaken over an eight-year period from 1999 to 2006, with classification of cases according to the San Diego definition. Sudden and/or unexpected deaths in previously healthy infants due to asphyxia or infection were selected as controls.ResultsThere were 42 SIDS cases and 25 controls. The SIDS cases were aged from 1 to 42 weeks (mean: 16.26 ± 1.5 weeks) with a male to female ratio of 26:16. The control infants were aged from 3 to 48 weeks (mean: 19.24 ± 2.9 weeks) (P > 0.05) (M:F = 16:9) and included 13 cases of asphyxia and 12 cases of sepsis. Comparison of the brain-body weight ratios failed to demonstrate a significant difference: SIDS mean = 0.121 ± 0.003; control mean = 0.115 ± 0.003 (P > 0.05).ConclusionAlthough, there was a trend towards higher brain-body weight ratios in SIDS infants, this did not reach significance. The role of brain weight in the aetiology of SIDS remains controversial.
Authors:
Jane A Elliott; Robert Vink; Lisbeth Jensen; Roger W Byard
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-22
Journal Detail:
Title:  Medicine, science, and the law     Volume:  -     ISSN:  0025-8024     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400721     Medline TA:  Med Sci Law     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Discipline of Anatomy and Pathology, The University of Adelaide, Level 3 Medical School North Building, Frome Road, Adelaide, SA 5000, Australia.
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