Document Detail


Brain-typical creatinekinase in the serum of newborn infants with perinatal brain damage.
MedLine Citation:
PMID:  626076     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The normal values of serum-CK-activity in healthy newborns varied greatly (95% range: 4--165 U/l; 257 probands) and the borderline to pathological values was not sharp. Brain-typical CK-isoenzyme (CK-BB) could be detected in serum of 6 of 8 infants with perinatal brain damage by means of agar gel electrophoresis. The combination of neuropathological symptoms, increased total-serum-CK-activity, and significant amount of CK-BB in serum seemed to be a sure sign of severe CNS-damage in newborns.
Authors:
M Becker; K Menzel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta paediatrica Scandinavica     Volume:  67     ISSN:  0001-656X     ISO Abbreviation:  Acta Paediatr Scand     Publication Date:  1978 Mar 
Date Detail:
Created Date:  1978-04-17     Completed Date:  1978-04-17     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0000211     Medline TA:  Acta Paediatr Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  177-80     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Brain Diseases / enzymology*
Creatine Kinase / blood*
Electrophoresis, Agar Gel
Humans
Infant, Newborn
Infant, Newborn, Diseases / enzymology*
Isoenzymes / blood*
Chemical
Reg. No./Substance:
0/Isoenzymes; EC 2.7.3.2/Creatine Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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