| Brain transplants. A new approach to the therapy of neurodegenerative disease. | |
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MedLine Citation:
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PMID: 3047549 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is now a wealth of experimental evidence to suggest that transplantation to the brain may ameliorate a variety of neurologic and endocrine disorders. Many unanswered questions remain. Chief among these questions are the duration of any salutary effects and the potential long-term risks to the host CNS. Answers to these questions will only come with carefully controlled long-term clinical studies. Given the high incidence and devastating nature of many of these diseases, such studies will have enormous scientific and social impact. Regardless of the outcome, there is the potential for a greater understanding of the pathologic mechanisms underlying neurodegenerative diseases and, thus, the possibility that definitive therapies will be found as a result. |
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Authors:
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N Tulipan |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Review |
Journal Detail:
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Title: Neurologic clinics Volume: 6 ISSN: 0733-8619 ISO Abbreviation: Neurol Clin Publication Date: 1988 May |
Date Detail:
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Created Date: 1988-10-24 Completed Date: 1988-10-24 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8219232 Medline TA: Neurol Clin Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 405-20 Citation Subset: IM |
Affiliation:
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Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Medulla
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transplantation* Animals Brain / surgery Caudate Nucleus / surgery* Clinical Trials as Topic Disease Models, Animal Fetus Humans Nerve Tissue / transplantation Nervous System Diseases / therapy Parkinson Disease / therapy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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