Document Detail


Brain tissue levels in a fatal case of neonatal mepivacaine (Carbocaine) poisoning.
MedLine Citation:
PMID:  1127509     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A fatal case of mepivacaine poisoning in a newborn infant is reported. Regional brain tissue concentrations of mepivacaine were determined by a sensitive and specific gas chromatographic-mass spectrometric method. The brain tissue levels in this patient were higher than those previously reported, possibly due to alkalosis occurring several hours prior to the infant's death.
Authors:
W E Dodson; R E Hillman; L S Hillman
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  86     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1975 Apr 
Date Detail:
Created Date:  1975-07-18     Completed Date:  1975-07-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  624-7     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Anesthesia, Obstetrical / adverse effects
Brain Chemistry*
Cerebellum / analysis
Cerebral Cortex / analysis
Cervix Uteri
Chromatography, Gas
Exchange Transfusion, Whole Blood
Female
Fetal Heart
Heart Rate
Humans
Infant, Newborn
Infant, Newborn, Diseases / chemically induced*
Kidney / analysis
Liver / analysis
Mass Spectrometry
Medulla Oblongata / analysis
Mepivacaine / analysis,  blood,  poisoning*
Nerve Block / adverse effects
Pons / analysis
Pregnancy
Spinal Cord / analysis
Chemical
Reg. No./Substance:
96-88-8/Mepivacaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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