Document Detail


Brain-stem listeriosis: a comparison of SPECT and MRI findings.
MedLine Citation:
PMID:  17415328     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Listeria monocytogenes, although uncommon as a cause of illness in the general population, can result in serious illness when it affects pregnant women, neonates, the elderly, and immunocompromised individuals. Typically, it is a food-borne organism. This report describes a case of brain-stem listeriosis in a previously healthy 51-year-old woman. The diagnosis was based on clinical findings, the results of cerebrospinal fluid (CSF) analysis, CSF culture, and magnetic resonance imaging (MRI) findings. MRI demonstrated upper brain stem and cerebellar peduncle involvement. In addition, Tc-99m exametazime (HMPAO)-labeled single photon emission computed tomography (SPECT) of the brain revealed bilateral cerebellar hypoperfusion. Antibiotic therapy resulted in partial clinical recovery after 3 weeks. At the end of 6 months, brain-stem findings had nearly resolved. However, although minimal residual findings were observed on MRI at 6 months, bilateral diffuse cerebellar hypoperfusion remained on Tc-99m HMPAO brain SPECT.
Authors:
Sevki Sahin; Ayse S Arisoy; Aynur E Topkaya; Sibel Karsidag
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article     Date:  2006-12-06
Journal Detail:
Title:  MedGenMed : Medscape general medicine     Volume:  8     ISSN:  1531-0132     ISO Abbreviation:  MedGenMed     Publication Date:  2006  
Date Detail:
Created Date:  2007-04-06     Completed Date:  2007-07-18     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  100894134     Medline TA:  MedGenMed     Country:  United States    
Other Details:
Languages:  eng     Pagination:  47     Citation Subset:  IM    
Affiliation:
Department of Neurology, Faculty of Medicine, Maltepe University, Istanbul, Turkey. drsahin@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Ampicillin / pharmacology,  therapeutic use
Brain Stem / drug effects,  microbiology,  pathology*
Female
Humans
Listeria Infections / diagnosis*,  drug therapy
Listeria monocytogenes / drug effects
Magnetic Resonance Imaging / methods*
Middle Aged
Tomography, Emission-Computed, Single-Photon / methods*
Chemical
Reg. No./Substance:
69-53-4/Ampicillin
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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