Document Detail


Brain-specific proteins in the occipital cortex of rats housed in enriched and impoverished environments.
MedLine Citation:
PMID:  460519     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The occipital cortex was dissected from the brain of rats housed in either enriched or impoverished environment for four weeks. In environmentally enriched rats the weight of occipital cortex was found to be increased 5.7%, compared to environmentally impoverished rats, and the amount of protein was increased 6.0%. The amount of six nervous system-specific proteins was measured by crossed immunoelectrophoresis. Synaptin increased 4.7%, D3 increased 8.3%, and D1 increased 9.6%, whereas D2 was not significantly increased. Compared to D2, D3 and D1 were still increased significantly, although all were present in synaptosomal membrane fractions. The protein S-100 was increased 3.4% and the neuronal protein 14-3-2 was increased 12.2% for the cathodal component whereas the anodal component was not increased. The results were interpreted as representing delayed development of environment-dependent neurons in the environmentally impoverished rats.
Authors:
O S Jørgensen; E Bock
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurochemical research     Volume:  4     ISSN:  0364-3190     ISO Abbreviation:  Neurochem. Res.     Publication Date:  1979 Apr 
Date Detail:
Created Date:  1979-09-17     Completed Date:  1979-09-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7613461     Medline TA:  Neurochem Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  175-87     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Environment*
Male
Nerve Tissue Proteins / analysis*
Occipital Lobe / analysis*,  growth & development
Organ Size
Rats
S100 Proteins / analysis
Synaptic Vesicles / analysis
Synaptosomes / analysis
Time Factors
Chemical
Reg. No./Substance:
0/Nerve Tissue Proteins; 0/S100 Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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