| Brain regions expressing Fos during thermoregulatory behavior in rats. | |
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MedLine Citation:
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PMID: 12893652 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We surveyed the neural substrata for behavioral thermoregulation with immunohistochemical analysis of the expression of Fos protein in the rat brain. We used an operant system in which a rat exposed to heat (40 degrees C) could get cold air (0 degrees C) for 30 s when it moved into the reward area. Rats moved in and out of the reward area of the system periodically and thus maintained their body temperature at a normal level. In the rats performing heat escape behavior (active group), strong Fos immunoreactivity (Fos-IR) was found in the median preoptic nucleus (MnPO), parastrial nucleus (PS), and dorsomedial hypothalamus (DMH) compared with the controls. Another group of rats (passive group) were given the same temperature changes, regardless of the rat's movement, as those obtained by rats of the active group. Fos-IR in the MnPO was also seen in this group. The present results suggest that the PS and DMH play an important role in the genesis of thermoregulatory behavior, whereas the MnPO may be important for detecting changes in ambient and/or body temperatures. |
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Authors:
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Megumi Maruyama; Maiko Nishi; Masahiro Konishi; Yuko Takashige; Kei Nagashima; Toshikazu Kiyohara; Kazuyuki Kanosue |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2003-07-31 |
Journal Detail:
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Title: American journal of physiology. Regulatory, integrative and comparative physiology Volume: 285 ISSN: 0363-6119 ISO Abbreviation: Am. J. Physiol. Regul. Integr. Comp. Physiol. Publication Date: 2003 Nov |
Date Detail:
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Created Date: 2003-10-14 Completed Date: 2003-11-21 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 100901230 Medline TA: Am J Physiol Regul Integr Comp Physiol Country: United States |
Other Details:
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Languages: eng Pagination: R1116-23 Citation Subset: IM; S |
Affiliation:
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School of Sport Sciences, Waseda University, Mikajima 2-579-15, Tokorozawa, Saitama 359-1192, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Behavior, Animal / physiology Body Temperature Regulation / physiology* Conditioning, Operant / physiology Dorsomedial Hypothalamic Nucleus / physiology* Hot Temperature Male Preoptic Area / physiology* Proto-Oncogene Proteins c-fos / metabolism* Rats Rats, Wistar |
| Chemical | |
Reg. No./Substance:
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0/Proto-Oncogene Proteins c-fos |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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