Document Detail

Brain monoamines following castration of aggressive muricidal rats.
MedLine Citation:
PMID:  7682660     Owner:  NLM     Status:  MEDLINE    
The effect of castration on the levels of brain monoamines and their metabolites has been investigated in rats which became or did not become muricidal following long-term isolation. Fourteen brain areas were explored: olfactory bulbs (OB), olfactory tubercles (OT), septum (Se), striatum (Sr), amygdala (A), thalamus (Th), hypothalamus (Hy), hippocampus (Hi), superior colliculus (SC), inferior colliculus (IC), raphe (Ra), pons-medulla (PM), frontal cortex (FC), temporal cortex (TC) and parietal cortex (PC). Except in the raphe of non muricidal rats and in the striatum of muricidal animals, all other areas examined demonstrate some changes of monoamines neurotransmitter or their metabolites after castration. The strongest changes, always increases, were found in the thalamus. In several brain areas, the changes occurring after castration, differ quantitatively and qualitatively in muricidal and non-muricidal rats.
A Rastegar; L Ciesielski; S Simler; M Messripour; P Mandel
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurochemical research     Volume:  18     ISSN:  0364-3190     ISO Abbreviation:  Neurochem. Res.     Publication Date:  1993 Apr 
Date Detail:
Created Date:  1993-05-19     Completed Date:  1993-05-19     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7613461     Medline TA:  Neurochem Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  471-7     Citation Subset:  IM    
Centre de Neurochimie due CNRS, Strasbourg, France.
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MeSH Terms
3,4-Dihydroxyphenylacetic Acid / metabolism
Biogenic Monoamines / metabolism*
Brain / metabolism*
Dopamine / metabolism
Hydroxyindoleacetic Acid / metabolism
Norepinephrine / metabolism
Rats, Wistar
Serotonin / metabolism
Social Isolation
Thalamus / metabolism
Reg. No./Substance:
0/Biogenic Monoamines; 102-32-9/3,4-Dihydroxyphenylacetic Acid; 50-67-9/Serotonin; 51-41-2/Norepinephrine; 54-16-0/Hydroxyindoleacetic Acid

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