Document Detail

Brain magnetic resonance imaging in non-alcoholic cirrhosis.
MedLine Citation:
PMID:  8850497     Owner:  NLM     Status:  MEDLINE    
Twenty-six patients with stable non-alcoholic cirrhosis and normal neurological examination were investigated by brain MRI (inversion recovery sequences) and compared with 16 controls. Brain MRI findings were correlated with the clinical and metabolic status of the patients and analysis of variance and, when necessary, co-variance was performed. Five of the patients (19%) and all 16 controls showed no MRI changes. Twelve patients (46%) showed moderately high signal in the globus pallidus (score 1), and nine (35%) very high signal (score 2). Analysis of variance showed that age was the only significant variable (P = 0.038). Analysis of co-variance after adjustment for age showed that high pallidal signal was correlated only to ammonia level (P = 0.02) but not to any other clinical or biological parameter. We conclude that T1 high intensity pallidal signal is common in non-alcoholic cirrhosis even when neurological examination is normal, but its significance remains unclear.
A Awada; S Sullivan; V Palkar; F Sbeih; R Naufal; S Al Rajeh
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of radiology     Volume:  21     ISSN:  0720-048X     ISO Abbreviation:  Eur J Radiol     Publication Date:  1995 Dec 
Date Detail:
Created Date:  1997-01-07     Completed Date:  1997-01-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  84-8     Citation Subset:  IM    
Division of Neurology, King Fahad National Guard Hospital, Riyadh, Saudi Arabia.
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MeSH Terms
Age Factors
Ammonia / metabolism
Analysis of Variance
Bilirubin / blood
Brain / metabolism,  pathology*
Globus Pallidus / metabolism,  pathology
Hepatitis B / complications
Hepatitis C / complications
Image Enhancement
Liver Cirrhosis* / blood,  etiology,  metabolism
Magnetic Resonance Imaging*
Middle Aged
Neurologic Examination
Prospective Studies
Prothrombin Time
Schistosomiasis / complications
Serum Albumin / analysis
Reg. No./Substance:
0/Serum Albumin; 635-65-4/Bilirubin; 7664-41-7/Ammonia

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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