Document Detail

Brain injury in the infant: the old, the new, and the uncertain.
MedLine Citation:
PMID:  16714917     Owner:  NLM     Status:  MEDLINE    
Although neonatal brain injury occurs most frequently after a perinatal hypoxic-ischemic insult, recently studies have noted that variable causes such as metabolic and reperfusion events can result in, or aggravate, a brain insult. Current data suggest that about 2 to 5 of 1,000 live births in the United States and more so in developing countries experience a brain injury Approximately 20% to 40% of infants who survive the brain injury develop significant neurological and developmental impairments. The resulting impact on the child, family, and society presents a formidable challenge to health care professionals. Although several important insights have been gained in the last several years about the epidemiology, diagnosis, and mechanism of brain injury, management remains mostly a cocktail of controversial trials. This article provides a comprehensive review of the pathology, clinical manifestations, and timely management of infants with brain injury.
Lina Kurdahi Badr Zahr; Isabell Purdy
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of perinatal & neonatal nursing     Volume:  20     ISSN:  0893-2190     ISO Abbreviation:  J Perinat Neonatal Nurs     Publication Date:    2006 Apr-Jun
Date Detail:
Created Date:  2006-05-22     Completed Date:  2006-07-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8801387     Medline TA:  J Perinat Neonatal Nurs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  163-75; quiz 176-7     Citation Subset:  N    
School of Nursing, Azusa Pacific University, and David Geffen School of Medicine, University of California at Los Angeles, CA, USA.
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MeSH Terms
Asphyxia Neonatorum / complications
Brain / anatomy & histology,  embryology,  growth & development
Cerebral Hemorrhage / complications
Cerebral Ventricles
Early Diagnosis
Fetal Development
Fetal Hypoxia
Fluid Therapy
Hypothermia, Induced
Hypoxia-Ischemia, Brain* / diagnosis,  etiology,  therapy
Infant, Newborn
Intensive Care, Neonatal / methods*
Neonatal Nursing / methods*
Neurologic Examination
Neuronal Plasticity
Neuroprotective Agents / therapeutic use
Nurse's Role
Nursing Assessment
Patient Discharge
Risk Factors
Severity of Illness Index
Reg. No./Substance:
0/Neuroprotective Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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