Document Detail


Brain in a Box.
MedLine Citation:
PMID:  23234471     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The brain, despite its sophistication, resides in a rudimentary container. The rigid cranium restricts enlargement of its contents, so that intracranial pressure rises rapidly as brain volume expands. When pressure becomes greatly elevated, cerebral blood flow is impeded, and the result is brain death. For this reason, the reduction of elevated intracranial pressure is a central theme in the management of traumatic brain injury, cerebral hemorrhage, and most other intracranial mass lesions. The widely adopted recommendation of the Brain Trauma Foundation is to keep intracranial pressure below 20 mm Hg in order to avoid poor outcome(1); adherence requires that . . .
Authors:
Allan H Ropper
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-12
Journal Detail:
Title:  The New England journal of medicine     Volume:  -     ISSN:  1533-4406     ISO Abbreviation:  N. Engl. J. Med.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0255562     Medline TA:  N Engl J Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
From the Department of Neurology, Brigham and Women's Hospital, Boston.
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