Document Detail


Brain changes on computed tomography following metrizamide myelography. Significance and therapeutic implications.
MedLine Citation:
PMID:  3787318     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Three cases of seizures and marked behavioral changes that occurred after intrathecal metrizamide administration are reported. In each case a cranial computed tomographic scan obtained within 24 hours of the ictus showed hyperdensity of the gray matter, and created an optical illusion of diffuse white matter edema. The literature on adverse reactions and their pathogenesis and on brain parenchymal penetration of metrizamide is reviewed.
Authors:
R S Centeno; M Sovak; D B Hackney; S R Garfin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Spine     Volume:  11     ISSN:  0362-2436     ISO Abbreviation:  Spine     Publication Date:    1986 Jul-Aug
Date Detail:
Created Date:  1986-12-30     Completed Date:  1986-12-30     Revised Date:  2009-07-09    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  509-12     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Brain / drug effects,  radiography*
Humans
Male
Metrizamide / adverse effects*,  diagnostic use
Middle Aged
Molecular Weight
Myelography*
Osmolar Concentration
Seizures / chemically induced*
Tomography, X-Ray Computed*
Chemical
Reg. No./Substance:
31112-62-6/Metrizamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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