| Brain biochemistry using magnetic resonance spectroscopy: relevance to psychiatric illness in the elderly. | |
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MedLine Citation:
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PMID: 10593699 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Magnetic resonance spectroscopy (MRS) allows for the noninvasive study of cerebral biochemistry. It has been used to investigate cerebral metabolic changes associated with mental illness in vivo and in vitro. In this review, we will discuss the application of MRS to psychiatric illness in the elderly. Following a brief description of the basic principles of MRS, the use of phosphorus (31P) and proton (1H) MRS to enable a better understanding of normal brain aging, dementia (Alzheimer's disease, multiple subcortical infarct dementia, Down syndrome, frontotemporal dementia, vascular dementia, age-associated memory impairment, and other dementias), major depression, and electroconvulsive therapy is detailed. |
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Authors:
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C M Moore; B B Frederick; P F Renshaw |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of geriatric psychiatry and neurology Volume: 12 ISSN: 0891-9887 ISO Abbreviation: J Geriatr Psychiatry Neurol Publication Date: 1999 |
Date Detail:
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Created Date: 2000-04-11 Completed Date: 2000-04-11 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 8805645 Medline TA: J Geriatr Psychiatry Neurol Country: CANADA |
Other Details:
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Languages: eng Pagination: 107-17 Citation Subset: IM |
Affiliation:
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Brain Imaging Center, McLean Hospital, Belmont, Massachusetts 02478, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aging / metabolism*, pathology Brain / metabolism*, pathology, physiopathology Brain Chemistry Dementia / metabolism Depressive Disorder, Major / metabolism Electroconvulsive Therapy Humans Magnetic Resonance Spectroscopy / methods* Mental Disorders / metabolism*, pathology, physiopathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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