Document Detail

Brain abscesses complicating Staphylococcus aureus sepsis in a premature infant.
MedLine Citation:
PMID:  15750759     Owner:  NLM     Status:  MEDLINE    
Brain abscess is a rare complication of staphylococcal bacteremia in infants. Here we present a case of a premature infant who developed multiple brain abscesses 12 weeks following an episode of inadequately treated Staphylococcus aureus sepsis. The abscess developed in the absence of trauma, prior surgery, cyanotic heart disease, or immune defect. The initial staphylococcal isolate exhibited identical pulsed-field gel electrophoresis pattern with that of the isolate cultured from abscess aspirate. The infant was successfully treated by surgical drainage and administration of antibiotics for 12 weeks, initially teicoplanin and meropenem followed by trimethoprim/sulfamethoxazole, without neurological or developmental sequelae. Staphylococcal bacteremia in neonates should be vigorously treated to prevent life-threatening complications.
G Vartzelis; M Theodoridou; G L Daikos; H Dellagrammaticas; V P Syriopoulou
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Infection     Volume:  33     ISSN:  0300-8126     ISO Abbreviation:  Infection     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-03-07     Completed Date:  2005-05-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0365307     Medline TA:  Infection     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  36-8     Citation Subset:  IM    
First Dept. of Pediatrics, Aghia Sophia Children's Hospital, Athens University, Thivon and Levadias Streets, GR-115 27 Athens, Greece.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use
Brain Abscess / drug therapy,  microbiology*,  surgery
Infant, Newborn
Infant, Premature, Diseases / microbiology*
Sepsis / complications*,  drug therapy
Staphylococcal Infections* / drug therapy
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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