Document Detail


Brain abscess in Korean children: A 15-year single center study.
MedLine Citation:
PMID:  21189932     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
PURPOSE: A brain abscess is a serious disease of the central nerve system. We conducted this study to summarize the clinical manifestations and outcomes of brain abscesses.
METHODS: A retrospective chart review of pediatric patients diagnosed with brain abscesses from November 1994 to June 2009 was performed at Samsung Medical Center, Seoul, Korea.
RESULTS: Twenty-five patients were included in this study. On average, 1.67 cases per year were identified and the median age was 4.3 years. The common presenting clinical manifestations were fever (18/25, 72%), seizure (12/25, 48%), altered mental status (11/25, 44%), and signs of increased intracranial pressure (9/25, 36%). A total of 14 (56%) patients had underlying illnesses, with congenital heart disease (8/25, 32%) as the most common cause. Predisposing factors were identified in 15 patients (60%). The common predisposing factors were otogenic infection (3/25, 12%) and penetrating head trauma (3/25, 12%). Causative organisms were identified in 64% of patients (16/25). The causative agents were S. intermedius (n=3), S. aureus (n=3), S. pneumoniae (n=1), Group B streptococcus (n=2), E. coli (n=1), P. aeruginosa (n=1), and suspected fungal infection (n=5). Seven patients received medical treatment only while the other 18 patients also required surgical intervention. The overall fatality rate was 16% and 20% of patients had neurologic sequelae. There was no statistical association between outcomes and the factors studied.
CONCLUSION: Although uncommon, a brain abscess is a serious disease. A high level of suspicion is very important for early diagnosis and to prevent serious consequences.
Authors:
Cha Gon Lee; Seong Hun Kang; Yae Jean Kim; Hyung Jin Shin; Hyun Shin Choi; Jee Hun Lee; Mun Hyang Lee
Publication Detail:
Type:  Journal Article     Date:  2010-05-31
Journal Detail:
Title:  Korean journal of pediatrics     Volume:  53     ISSN:  2092-7258     ISO Abbreviation:  Korean J Pediatr     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-12-30     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101215374     Medline TA:  Korean J Pediatr     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  648-52     Citation Subset:  -    
Affiliation:
Department of Pediatrics, School of Medicine, Sungkyunkwan University, Samsung Medical Center, Seoul, Korea.
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