| Brain SPECT imaging in Huntington's disease before and after therapy with olanzapine. Case report. | |
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MedLine Citation:
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PMID: 10751925 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Olanzapine, an atypical antipsychotic drug, was administered to a patient with Huntington's disease (HD) with marked choreiform movements. Brain SPECT with 99mTc-HMPAO was performed before and after treatment. Brain SPECT imaging has been performed in patients with HD in order to determine the status of basal ganglia perfusion. The use of brain SPECT with 99mTc-HMPAO before and after treatment in patients with HD has not been yet reported. The marked hypoperfusion of the basal ganglia on brain SPECT performed before therapy with olanzapine improved significantly after treatment. |
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Authors:
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E C Etchebehere; M C Lima; W Passos; J A Maciel Júnior; A O Santos; C D Ramos; E E Camargo |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Arquivos de neuro-psiquiatria Volume: 57 ISSN: 0004-282X ISO Abbreviation: Arq Neuropsiquiatr Publication Date: 1999 Sep |
Date Detail:
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Created Date: 2000-04-20 Completed Date: 2000-04-20 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0125444 Medline TA: Arq Neuropsiquiatr Country: BRAZIL |
Other Details:
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Languages: eng Pagination: 863-6 Citation Subset: IM |
Affiliation:
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Department of Radiology, Faculdade de Ciências Médicas (FCM) da Universidade Estadual de Campinas (UNICAMP), Brazil. elba@mn-d.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antipsychotic Agents / therapeutic use* Benzodiazepines Brain / radionuclide imaging* Female Humans Huntington Disease / drug therapy*, radionuclide imaging Pirenzepine / analogs & derivatives*, therapeutic use Radiopharmaceuticals / diagnostic use Technetium Tc 99m Exametazime / diagnostic use Tomography, Emission-Computed, Single-Photon* |
| Chemical | |
Reg. No./Substance:
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0/Antipsychotic Agents; 0/Radiopharmaceuticals; 100504-35-6/Technetium Tc 99m Exametazime; 12794-10-4/Benzodiazepines; 132539-06-1/olanzapine; 28797-61-7/Pirenzepine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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