| Brain F-18 Fluorocholine PET/CT for the assessment of optic pathway glioma in neurofibromatosis-1. | |
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MedLine Citation:
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PMID: 20838306 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 22-year-old man diagnosed with neurofibromatosis-I was admitted to the neurology department because of progressive hemianopsia and chronic headache. Magnetic resonance imaging, magnetic resonance spectroscopy (MRS), and F-18 fluorocholine revealed a splenial mass with imaging features compatible with malignant astrocytoma. At follow-up examination, the sharp decrease in F-18 fluorocholine uptake and in choline/creatine ratio supported a conservative management. Molecular imaging of optic pathway gliomas may be a valuable tool in the selection of therapeutic options. |
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Authors:
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Francesco Roselli; Nicola M Pisciotta; Maria S Aniello; Artor Niccoli-Asabella; Giovanni Defazio; Paolo Livrea; Giuseppe Rubini |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Clinical nuclear medicine Volume: 35 ISSN: 1536-0229 ISO Abbreviation: Clin Nucl Med Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-14 Completed Date: 2010-12-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7611109 Medline TA: Clin Nucl Med Country: United States |
Other Details:
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Languages: eng Pagination: 838-9 Citation Subset: IM |
Affiliation:
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Department of Neurological and Psychiatric Sciences, University of Bari, Bari, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Brain*
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radiography,
radionuclide imaging Choline / analogs & derivatives*, diagnostic use Glioma / diagnosis*, radiography, radionuclide imaging Humans Male Neurofibromatosis 1 / diagnosis*, radiography, radionuclide imaging Optic Nerve* Positron-Emission Tomography* Tomography, X-Ray Computed* Young Adult |
| Chemical | |
Reg. No./Substance:
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0/fluorocholine; 62-49-7/Choline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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