Document Detail


Brain evolution: microcephaly genes weigh in.
MedLine Citation:
PMID:  20219177     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The role of microcephaly genes in normal variation in human brain size has been controversial. New studies show that a link does exist and imply sex-specificity in microcephaly gene action during neurogenesis.
Authors:
Stephen H Montgomery; Nicholas I Mundy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current biology : CB     Volume:  20     ISSN:  1879-0445     ISO Abbreviation:  Curr. Biol.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-11     Completed Date:  2010-07-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9107782     Medline TA:  Curr Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  R244-6     Citation Subset:  IM    
Affiliation:
Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK.
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MeSH Terms
Descriptor/Qualifier:
Animals
Brain / growth & development*
Evolution
Female
Gene Expression Regulation, Developmental / physiology
Humans
Microcephaly / genetics*
Nerve Tissue Proteins / genetics,  metabolism
Polymorphism, Single Nucleotide
Chemical
Reg. No./Substance:
0/ASPM protein, human; 0/MCPH1 protein, human; 0/Nerve Tissue Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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